Medical CBD Hemp &
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ACNE
Acne and CBD Hemp Oil Research
Acne and CBD Hemp Oil Research
- The safety and efficacy of 3% Cannabis seeds extract cream for reduction of human cheek skin sebum and erythema content
- CBD as a Treatment for Acne?
- CBD exerts sebostatic and antiinflammatory effects on human sebocytes
- The endocannabinoid system of the skin in health and disease
- Endocannabinoids enhance lipid synthesis and apoptosis of human sebocytes via cannabinoid receptor-2-mediated signaling
- Endocannabinoid signaling and epidermal differentiation
- Differential effectiveness of selected non-psychotropic phytocannabinoids on human sebocyte functions
ADD & ADHD & HYPERACTIVITY & ATTENTION DISORDERS
Hyperactivity & Attention Disturbances and Cannabinoids
Hyperactivity & Attention Disturbances and Cannabinoids
- Searching for a Neurobiological Basis for Self-Medication Theory in ADHD Comorbid With Substance Use Disorders
- CBD and clozapine reverse MK-801-induced deficits in social interaction and hyperactivity in Sprague-Dawley rats
- Subtypes of ADHD and cannabis use
- Childhood and current ADHD symptom dimensions are associated with more severe cannabis outcomes in college students
- Oral delta 9-THC improved refractory Gilles de la Tourette syndrome in an adolescent by increasing intracortical inhibition
- Fitness to drive in spite (because) of THC
- ADHD Is Highly Prevalent in Patients Seeking Treatment for Cannabis Use Disorders
- A Qualitative Analysis of Online Forum Discussions on Cannabis Use and ADHD
- Cannabinoids in attention-deficit/hyperactivity disorder: a randomised-controlled trial
ADDICTIONS TO DRUGS & ALCOHOL
Addictions and CBD Research
Addictions and CBD Research
- CBD as an Intervention for Addictive Behaviors
- CBD reduces cigarette consumption in tobacco smokers
- Inhibition of monoacylglycerol lipase enzyme reduces nicotine withdrawal
- CBD inhibits the reward-facilitating effect of morphine
- Cannabidiol, a nonpsychotropic component of cannabis, inhibits cue-induced heroin seeking and normalizes discrete mesolimbic neuronal disturbances
- Differential effect of cannabinol and cannabidiol on THC-induced responses during abstinence in morphine-dependent rats
- Impact of Cannabis Use during Stabilization on Methadone Maintenance Treatment
- Medical cannabis laws and opioid analgesic overdose mortality in the United States, 1999-2010
- Dysregulation of cannabinoid CB1 receptor and associated signaling networks in brains of cocaine addicts and cocaine-treated rodents
- Comparison of CBD, antioxidants, and diuretics in reversing binge ethanol-induced neurotoxicity
- Transdermal delivery of CBD attenuates binge alcohol-induced neurodegeneration in a rodent model of an alcohol use disorder
- CBD for the treatment of cannabis withdrawal syndrome
- Cannabis use disorders are comparatively prevalent among nonwhite racial/ethnic groups and adolescents
- CBD Counteracts Amphetamine-Induced Neuronal and Behavioral Sensitization of the Mesolimbic Dopamine Pathway
- CBD regulation of emotion and emotional memory processing: relevance for treating anxiety-related and substance abuse disorders
ALZHEIMER'S & DEMENTIA
Memory Loss and Cannabinoid Research
ALZHEIMER'S & DEMENTIA
Memory Loss and Cannabinoid Research
- Cannabinoids for the Treatment of Agitation and Aggression in Alzheimer’s Disease
- The therapeutic potential of the endocannabinoid system for Alzheimer’s disease
- Endocannabinoid signalling in Alzheimer’s disease
- A molecular link between the active component of marijuana and Alzheimer’s disease pathology
- Neuroprotective effect of CBD... on beta-amyloid-induced toxicity in PC12 cells
- The Potential Therapeutic Effects of THC on Alzheimer’s Disease
- The Role of Endocannabinoid Signaling in the Molecular Mechanisms of Neurodegeneration in Alzheimer’s Disease
- Cannabinoids for the treatment of dementia
- CBD in vivo blunts beta-amyloid induced neuroinflammation by suppressing IL-1beta and iNOS expression
- CBD: A promising drug for neurodegenerative disorders?
- Cannabinoid receptor 1 deficiency in a mouse model of Alzheimer’s disease leads to enhanced cognitive impairment despite of a reduction in amyloid deposition
- The role of the endocannabinoid system in Alzheimer’s disease
- The role of phytochemicals in the treatment and prevention of dementia
- Cannabinoids for the treatment of dementia
- Cannabidiol Promotes Amyloid Precursor Protein Ubiquitination and Reduction of Beta Amyloid Expression in SHSY5YAPP+ Cells Through PPARγ Involvement
- Cannabinoids for treatment of Alzheimer’s disease: moving toward the clinic
- Can Marijuana Prevent Alzheimer’s?
- Safety and Efficacy of Medical Cannabis Oil for Behavioral and Psychological Symptoms of Dementia
- Cannabinoids for the Treatment of Agitation and Aggression in Alzheimer's Disease
- Natural Phytochemicals in the Treatment and Prevention of Dementia: An Overview
- Delineating the Efficacy of a Cannabis-Based Medicine at Advanced Stages of Dementia in a Murine Model
- CBD Modulates the Expression of Alzheimer’s Disease-Related Genes in Mesenchymal Stem Cells
ANXIETY & STRESS
Medical Research Publications
Stress and CBD Research
Medical Research Publications
- A Systematic review of plant-derived natural compounds for Anxiety Disorders
- Does Cannabidiol Protect Against Adverse Psychological Effects of THC?
- Plant-based medicines for anxiety disorders, part 2: a review of clinical studies with supporting preclinical evidence
- Cannabinoid-related agents in the treatment of anxiety disorders: current knowledge and future perspectives
- Distinct Effects of ?9-Tetrahydrocannabinol and Cannabidiol on Neural Activation During Emotional Processing
- What studies say about Hemp CBD
- CBD Oil for Anxiety: Is Cannabidiol an Effective Treatment?
- Cannabidiol exhibits anxiolytic but not antipsychotic property evaluated in the social interaction test
- Endocannabinoid system and mood disorders: Priming a target for new therapies
- Effects of Cannabidiol (CBD) on Regional Cerebral Blood Flow
- Cannabidiol, a Cannabis sativa constituent, as an anxiolytic drug
- Neural basis of anxiolytic effects of cannabidiol (CBD) in generalized social anxiety disorder: a preliminary report
- Cannabidiol Reduces the Anxiety Induced by Simulated Public Speaking in Treatment-Naïve Social Phobia Patients
- Dr. Allan Frankel on Anxiety and Cannabidiol
- CBD Gum Canchew helps Anxiety Depersonolization Derealization
- CBD as an anxiolytic drug
- Antidepressant-Like and Anxiolytic-Like Effects of Cannabidiol: A Chemical Compound of Cannabis Sativa
- CBD reduces the anxiety induced by simulated public speaking in treatment-naïve social phobia patients
- Neural basis of anxiolytic effects of CBD in generalized social anxiety disorder
- Central anandamide deficiency predicts stress-induced anxiety: behavioral reversal through endocannabinoid augmentation
- Effects of CBD on regional cerebral blood flow
- The anxiolytic-like effects of cannabidiol injected into the bed nucleus of the stria terminalis are mediated by 5-HT1Areceptors
- The anxiolytic effect of CBD on chronically stressed mice depends on hippocampal neurogenesis: involvement of the endocannabinoid system
- Plant-based medicines for anxiety disorders, part 2
- A systematic review of plant-derived natural compounds for anxiety disorders
- The Endocannabinoid System and Anxiety
- CBD regulation of emotion and emotional memory processing: relevance for treating anxiety-related and substance abuse disorders
- Effect of prior foot shock stress and Δ9-tetrahydrocannabinol, cannabidiolic acid, and cannabidiol on anxiety-like responding in the light-dark emergence test in rats
Stress and CBD Research
- CBD Enhances Fracture Healing and Stimulates Lysyl Hydroxylase Activity in Osteoblasts
- Cannabinoid receptors as target for treatment of osteoporosis: A tale of two therapies
- Cannabinoids and bone: Friend or foe?
- Cannabinoid receptor type 1 protects against age-related osteoporosis by regulating osteoblast and adipocyte differentiation in marrow stromal cells
- Cannabinoids and the skeleton: From marijuana to reversal of bone loss
- The endovanilloid/endocannabinoid system: A new potential target for osteoporosis therapy
- The endovanilloid/endocannabinoid system in human osteoclasts: Possible involvement in bone formation and resorption
- Endocannabinoids and the regulation of bone metabolism
- Cannabinoid receptors and the regulation of bone mass
- Natural products as alternative treatments for metabolic bone disorders and for maintenance of bone health
- Peripheral cannabinoid receptor, CB2, regulates bone mass
- Regulation of bone mass, bone loss and osteoclast activity by cannabinoid receptors
- Long-chain polyunsaturated fatty acids may mutually benefit both obesity and osteoporosis
- Skeletal lipidomics: Regulation of bone metabolism by fatty acid amide family
ARTHRITIS & RHEUMATISM
CBD oil and arthritis medical research
CBD oil and arthritis medical research
- The abnormal cannabidiol analogue O-1602 reduces nociception in a rat model of acute arthritis via the putative cannabinoid receptor GPR55.
- Oral anti-inflammatory activity of cannabidiol, a non-psychoactive constituent of cannabis, in acute carrageenan-induced inflammation in the rat paw.
- Cannabidiol as an emergent therapeutic strategy for lessening the impact of inflammation on oxidative stress.
- Therapeutic potential of cannabinoid-based drugs.
- Involvement of the Endocannabinoid System in Osteoarthroid Pain
- Transdermal cannabidiol reduces inflammation and pain-related behaviours in a rat model of arthritis.
- Cannabis and Arthritis: THC and CBD to the Rescue
- Medical Cannabis for Rheumatoid Arthritis?
- The nonpsychoactive cannabis constituent cannabidiol is an oral anti-arthritic therapeutic in murine collagen-induced arthritis
- The use of a cannabis-based medicine (Sativex) in the treatment of pain caused by rheumatoid arthritis.
- Cannabidiol (CBD): Fighting Inflammation & Aggressive Forms of Cancer
- Preliminary assessment of the efficacy, tolerability and safety of a cannabis-based medicine (Sativex) in the treatment of pain caused by rheumatoid arthritis
- Cannabis constituent cannabidiol is an oral anti-arthritic therapeutic
- Rheumatoid Arthritis-NORML
- CBD Weekly: CBD and Arthritis
- Medical Cannabis Can Help Arthritis Patients
- Rheumatoid Arthritis patient explains How Cannabis Benefits his Life!!
- Cannabis 101: What is the difference between Indica vs. Sativa vs. Hybrid
- Preliminary assessment of the efficacy, tolerability and safety of a cannabis-based medicine (Sativex) in the treatment of pain caused by rheumatoid arthritis
- The nonpsychoactive cannabis constituent cannabidiol is an oral anti-arthritic therapeutic in murine collagen-induced arthritis
- Involvement of the endocannabinoid system in osteoarthritis pain
- The abnormal cannabidiol analogue O-1602 reduces nociception in a rat model of acute arthritis via the putative cannabinoid receptor GPR55
AUTISM
NEW! Israeli CBD oil and Autism Clinical Trial - Read more HERE
CBD oil and autism medical research
- Cannabinoid receptor type 2, but not type 1, is up-regulated in peripheral blood mononuclear cells of children affected by autistic disorders
- A novel approach to the symptomatic treatment of autism
- Consequences of cannabinoid and monoaminergic system disruption in a mouse model of autism spectrum disorders
- Targeting the endocannabinoid system in the treatment of fragile X syndrome
- Cannabis spray treatment helps 9-year-old with Autism learn to speak
- Cannabidiol seems to help with autism in young patients
- What happened when they treated autistic children with medical cannabis
- Cannabidiol might help treat autism
- Desperate parents of autistic children trying cannabis
- Mutations found in individuals with autism interfere with endocannabinoid signaling in the brain
- The autism and compassionate care connection
- Endocannabinoid Signaling in Autism
- Mutations found in individuals with autism interfere with endocannabinoid signaling in the brain
- Cannabinoid receptor type 2, but not type 1, is up-regulated in peripheral blood mononuclear cells of children affected by autistic disorders
- A novel approach to the symptomatic treatment of autism
- Consequences of cannabinoid and monoaminergic system disruption in a mouse model of autism spectrum disorders
- Targeting the endocannabinoid system in the treatment of fragile X syndrome
- Deficient adolescent social behavior following early-life inflammation is ameliorated by augmentation of anandamide signaling
BONE DISEASEBONE DISEASE & OSTEOPOROSIS
Bone Fractures
- Scientists Discover Marijuana Helps Heal Broken Bones, & Even Makes Them Stronger
- "We found that CBD alone makes bones stronger during healing, enhancing the maturation of the collagenous matrix, which provides the basis for new mineralization of bone tissue," said Dr. Gabet. "After being treated with CBD, the healed bone will be harder to break in the future."
- CBD and Bone Fractures Medical Study
- Cannabis Found To Heal Broken Bones, But Schedule 1 Status Makes Further Research Into Medical Marijuana Difficult
- Studies Suggest Cannabis can Treat Broken Bones and Bone Diseases
- No bones about it: Cannabis may be used to treat fractures
- CBD Enhances Fracture Healing and Stimulates Lysyl Hydroxylase Activity in Osteoblasts
- Cannabinoid receptors as target for treatment of osteoporosis: A tale of two therapies
- Cannabinoids and bone: Friend or foe?
- Cannabinoid receptor type 1 protects against age-related osteoporosis by regulating osteoblast and adipocyte differentiation in marrow stromal cells
- Cannabinoids and the skeleton: From marijuana to reversal of bone loss
- The endovanilloid/endocannabinoid system: A new potential target for osteoporosis therapy
- The endovanilloid/endocannabinoid system in human osteoclasts: Possible involvement in bone formation and resorption
- Endocannabinoids and the regulation of bone metabolism
- Cannabinoid receptors and the regulation of bone mass
- Natural products as alternative treatments for metabolic bone disorders and for maintenance of bone health
- Peripheral cannabinoid receptor, CB2, regulates bone mass
- Regulation of bone mass, bone loss and osteoclast activity by cannabinoid receptors
- Long-chain polyunsaturated fatty acids may mutually benefit both obesity and osteoporosis
- Skeletal lipidomics: Regulation of bone metabolism by fatty acid amide family
CANCER CELLS
CBD oil and Cancer Articles
- Cannabidiol, a non-psychoactive cannabinoid compound, inhibits proliferation and invasion in U87-MG and T98G glioma cells through a multitarget effect.
- Gamma-irradiation enhances apoptosis induced by cannabidiol, a non-psychotropic cannabinoid, in cultured HL-60 myeloblastic leukemia cells.
- Inhibition of colon carcinogenesis by a standardized Cannabis sativa extract with high content of cannabidiol.
- Cannabidiol-Induced Apoptosis in Human Leukemia Cells: A Novel Role of Cannabidiol in the Regulation of p22phox and Nox4 Expression
- Triggering of the TRPV2 channel by cannabidiol sensitizes glioblastoma cells to cytotoxic chemotherapeutic agents
- Antitumor Activity of Plant Cannabinoids with Emphasis on the Effect of Cannabidiol on Human Breast Carcinoma
- Cannabinoids for Cancer Treatment: Progress and Promise
- Cannabidiol Induces Programmed Cell Death in Breast Cancer Cells by Coordinating the Cross-talk between Apoptosis and Autophagy
- Cannabidiol inhibits growth and induces programmed cell death in kaposi sarcoma-associated herpesvirus-infected endothelium.
- Cannabidiol as a novel inhibitor of Id-1 gene expression in aggressive breast cancer cells
- Cannabis and Cancer, Pt. 3: How THC and CBD work on cancer cells
- Cannabis and Cannabinoids – National Cancer Institute
- Pot compound seen as tool against cancer
- Cannabidiol inhibits growth and induces programmed cell death in kaposi sarcoma-associated herpesvirus-infected endothelium.
- How Cannabinoids Kill Cancer - Dennis Hill
- Cancer: Do cannabinoids cure cancer by Dr Manuel Guzmán
- Marijuana And Cancer
- Medical Marijuana Stops Spread of Breast Cancer – NBC NEWS
- Cannabis vs Cancer Dr. Sanjay Gupta CNN – The CBD Discovery
- Watch what happens when Cannabis Oil is injected into Cancer cells
- Medical Marijuana Patient releases photos of massive tumors
- The Seth Group - The Action of Cannabinoids in Cancer Cells
Cancer & CBD by Category:
General
- CBD as potential anticancer drug
- CBD inhibits angiogenesis by multiple mechanisms
- The inhibitory effects of CBD on systemic malignant tumors
- CBD inhibits cancer cell invasion via upregulation of tissue inhibitor of matrix metalloproteinases-1
- Marijuana fights cancer and helps manage side effects
- In vitro and in vivo efficacy of non-psychoactive cannabidiol in neuroblastoma
- The Influence of Biomechanical Properties and Cannabinoids on Tumor Invasion
- Antitumorigenic targets of cannabinoids - current status and implications
- Cannabinoids - a new weapon against cancer?
- Cannabidiol enhances the inhibitory effects of delta9-THC on human glioblastoma cell proliferation and survival
- Antitumor effects of CBD, a nonpsychoactive cannabinoid, on human glioma cell lines
- Systematic review of the literature on clinical and experimental trials on the antitumor effects of cannabinoids in gliomas
- CBD inhibits human glioma cell migration through a cannabinoid receptor-independent mechanism
- Id-1 is a key transcriptional regulator of glioblastoma aggressiveness and a novel therapeutic target
- Triggering of the TRPV2 channel by cannabidiol sensitizes glioblastoma cells to cytotoxic chemotherapeutic agents
- CBD inhibits proliferation and invasion in U87-MG and T98G glioma cells through a multitarget effect
- Local delivery of cannabinoid-loaded microparticles inhibits tumor growth in a murine xenograft model of glioblastoma multiforme
- Synergistic responses between cannabidiol and DNA-damaging agents on the proliferation and viability of glioblastoma and neural progenitor cells in culture
- Cannabis improved survival of patients with aggressive brain cancer in controlled clinical study
- Antitumor activity of plant cannabinoids with emphasis on the effect of cannabidiol on human breast carcinoma
- CBD induces programmed cell death in breast cancer cells by coordinating the cross-talk between apoptosis and autophagy
- Pathways mediating the effects of CBD on the reduction of breast cancer cell proliferation, invasion, and metastasis
- CBD as a novel inhibitor of Id-1 gene expression in aggressive breast cancer cells
- Cannabidiolic acid, a major cannabinoid in fiber-type cannabis, is an inhibitor of MDA-MB-231 breast cancer cell migration
- CBD-A mediated selective down-regulation of c-fos in highly aggressive breast cancer MDA-MB-231 cells
- Chemopreventive effect of the non-psychotropic phytocannabinoid cannabidiol on experimental colon cancer
- Inhibition of colon carcinogenesis by a standardized Cannabis sativa extract with high content of CBD
- Induction of apoptosis by cannabinoids in prostate and colon cancer cells is phosphatase dependent
- Endocannabinoids in endocrine and related tumours
- A comparative study on CBD-induced apoptosis in murine thymocytes and EL-4 thymoma cells
- CBD-induced apoptosis in human leukemia cells: A novel role of cannabidiol in the regulation of p22phox and Nox4 expression
- CBD-Induced Apoptosis in Human Leukemia Cells
- Cannabidiol Reduces Leukemic Cell Size - But Is It Important?
- CBD inhibits lung cancer cell invasion and metastasis via intercellular adhesion molecule-1C
- COX-2 and PPAR-γ confer cannabidiol-induced apoptosis of human lung cancer cells
- Decrease of plasminogen activator inhibitor-1 may contribute to the anti-invasive action of CBD on human lung cancer cells
- Media ignored expert’s shocking findings that marijuana helps prevent lung cancer
- Multicenter, double-blind, randomized, placebo-controlled, parallel-group study of the efficacy, safety, and tolerability of THC:CBD extract and THC extract in patients with intractable cancer-related pain
- Nabiximols for opioid-treated cancer patients with poorly-controlled chronic pain: a randomized, placebo-controlled, graded-dose trial
- Marijuana extract helps prevent chemo pain
- Towards the use of non-psychoactive cannabinoids for prostate cancer
- In Vitro Anticancer Activity of Plant-Derived Cannabidiol on Prostate Cancer Cell Lines
- Induction of apoptosis by cannabinoids in prostate and colon cancer cells is phosphatase dependent
COLITIS & CROHN'S DISEASE & IRRITABLE BOWEL SYNDROME
Colitis and Crohn’s and CBD
- CBD in inflammatory bowel diseases: a brief overview
- Cannabis finds its way into treatment of Crohn’s disease
- CBD reduces intestinal inflammation through the control of neuroimmune axis
- Cannabidiol, a safe and non-psychotropic ingredient of the marijuana plant Cannabis sativa, is protective in a murine model of colitis
- The effects of Delta-tetrahydrocannabinol and CBD alone and in combination on damage, inflammation and in vitro motility disturbances in rat colitis
- Topical and systemic cannabidiol improves trinitrobenzene sulfonic acid colitis in mice
- Cannabinoids and the gut: New developments and emerging concepts
- Endocannabinoids and the gastrointestinal tract
- Cannabinoids and gastrointestinal motility: Animal and human studies
- Hergenrather presents study of Crohn’s patients as a template for clinical research on Cannabis
- Manipulation of the Endocannabinoid System in Colitis: A Comprehensive Review
- Low-Dose Cannabidiol Is Safe but Not Effective in the Treatment for Crohn’s Disease, a Randomized Controlled Trial.
- Cannabidiol in inflammatory bowel diseases: A brief overview
- CBD reduces intestinal inflammation through the control of neuroimmune axis
- Clinical endocannabinoid deficiency (CECD): Can this concept explain therapeutic benefits of cannabis in migraine, fibromyalgia, irritable bowel syndrome and other treatment-resistant conditions?
- Cannabinoid actions at TRPV channels: Effects on TRPV3 and TRPV4 and their potential relevance to gastrointestinal inflammation
- Therapeutic potential of cannabinoid-based drugs
- Beneficial effect of the non-psychotropic plant cannabinoid cannabigerol on experimental inflammatory bowel disease (Biochemical Pharmacology)
- CBD and the gut: New developments and emerging concepts
- Endocannabinoids and the gastrointestinal tract
- CBD and gastrointestinal motility
- Getting into the weed: the role of the endocannabinoid system in the brain-gut axis
- Cannabidiol in inflammatory bowel diseases: A brief overview
- CBD reduces intestinal inflammation through the control of neuroimmune axis
- Clinical endocannabinoid deficiency (CECD): Can this concept explain therapeutic benefits of cannabis in migraine, fibromyalgia, irritable bowel syndrome and other treatment-resistant conditions?
- Cannabinoid actions at TRPV channels: Effects on TRPV3 and TRPV4 and their potential relevance to gastrointestinal inflammation
- Therapeutic potential of cannabinoid-based drugs
- Beneficial effect of the non-psychotropic plant cannabinoid cannabigerol on experimental inflammatory bowel disease (Biochemical Pharmacology)
- CBD and the gut: New developments and emerging concepts
- Endocannabinoids and the gastrointestinal tract
- CBD and gastrointestinal motility
- Getting into the weed: the role of the endocannabinoid system in the brain-gut axis
- Cannabinoids and GI Disorders: Endogenous and Exogenous
DEPRESSION
CBD Oil and Depression Medical Research
- Antidepressant-like and Anxiolytic-like Effects of Cannabidiol: A Chemical Compound of Cannabis Sativa
- The Endocannabinoid System and the Treatment of Mood and Anxiety Disorders
- Endocannabinoid System Dysfunction in Mood and Related Disorders
- CBD relieves Depression faster than any other Anti-Depressant
- Cannabis as a treatment for Depression
- Home Remedies for Depression
- All in the Mind #4: How Cannabis Treats Depression
- CBD Relieves Depression Faster than Any Other Anti-Depressant
- Endocannabinoid system dysfunction in mood and related disorders
- Antidepressant-Like and Anxiolytic-Like Effects of CBD
- The endocannabinoid system and the treatment of mood and anxiety disorders
- Endocannabinoid signaling in the etiology and treatment of major depressive illness
- Antidepressant-like effects of cannabidiol in mice: Possible involvement of 5-HT1A receptors
- Putative role of endocannabinoid signaling in the etiology of depression and actions of antidepressants
- Antidepressant-like effect of delta9-tetrahydrocannabinol and other cannabinoids isolated from Cannabis sativa
- Circulating endocannabinoids and N-acyl ethanolamines are differentially regulated in major depression and following exposure to social stress
- Serum contents of endocannabinoids are correlated with blood pressure in depressed women
- The therapeutic potential of the endocannabinoid system for the development of a novel class of antidepressants
- Antidepressants and Changes in Concentration of Endocannabinoids and N-Acylethanolamines in Rat Brain Structures
- Cannabidiol induces rapid-acting antidepressant-like effects and enhances cortical 5-HT/glutamate neurotransmission: role of 5-HT1A receptors
- Prohedonic Effect of CBD in a Rat Model of Depression
- Antidepressant-like and anxiolytic-like effects of CBD
DIABETES & HIGH BLOOD GLUCOSE/SUGAR
Diabetes and CBD Research
- Diabetes Home / CBD-Conditions Relieved by Cannabidiol
- The impact of marijuana use on glucose, insulin, and insulin resistance among US adults
- CBD attenuates cardiac dysfunction, oxidative stress, fibrosis, and inflammatory and cell death signaling pathways in diabetic cardiomyopathy
- CBD lowers incidence of diabetes in non-obese diabetic mice
- Neuroprotective and blood-retinal barrier-preserving effects of CBD in experimental diabetes
- Cannabidiol arrests onset of autoimmune diabetes in NOD mice
- Diabetic retinopathy: Role of inflammation and potential therapies for anti-inflammation
- Cannabinoids alter endothelial function in the Zucker rat model of type 2 diabetes
- The endocannabinoid system in obesity and type 2 diabetes
- Cannabinoids and endocannabinoids in metabolic disorders with focus on diabetes
- The endocannabinoid system and plant-derived cannabinoids in diabetes and diabetic complications
- Cannabinoid-mediated modulation of neuropathic pain and microglial accumulation in a model of murine type I diabetic peripheral neuropathic pain
- Biochemical and immunohistochemical changes in delta-9-tetrahydrocannabinol-treated type 2 diabetic rats
- Efficacy and Safety of CBD and THC-V on Glycemic and Lipid Parameters in Patients With Type 2 Diabetes
- The impact of marijuana use on glucose, insulin, and insulin resistance among US adults
- The potential use of cannabidiol in the therapy of metabolic syndrome
- Cannabinoids and endocannabinoids in metabolic disorders with focus on diabetes
EYE DISEASE & DISORDERS
CBD and Eye Health Research
FIBROMYALGIA
Fibromyalgia and CBD Research
- Clinical endocannabinoid deficiency (CECD): Can this concept explain therapeutic benefits of cannabis in migraine, fibromyalgia, irritable bowel syndrome and other treatment-resistant conditions?
- Cannabis use in patients with fibromyalgia
- Cannabinoids for fibromyalgia
GENERAL HEALTH & CANNABINOIDS
General Health Benefits of CBD
- Safety and side effects of cannabidiol
- CBD: From an inactive cannabinoid to a drug with wide spectrum of action
- CBD as an emergent therapeutic strategy for lessening the impact of inflammation on oxidative stress
- CBD: An overview of some pharmacological aspects
- CBD: An overview of some chemical and pharmacological aspects
- The endocannabinoid system as an emerging target of pharmacotherapy
- Therapeutic potential of cannabinoid-based drugs
- Targeting the endocannabinoid system with cannabinoid receptor agonists
- Cannabis-based medicines–GW pharmaceuticals
- The therapeutic potential of cannabis and cannabinoids
- Emerging strategies for exploiting cannabinoid receptor agonists as medicines
- Therapeutic potential of cannabinoid-based drugs
- Cannabinoids in clinical practice
- Cannabinoids
- Pharmacology of cannabinoids
- Combined cannabinoid therapy via an oromucosal spray
- Non-psychotropic plant cannabinoids
- Opposite effects of delta-9-tetrahydrocannabinol and cannabidiol on human brain function and psychopathology
- Care and feeding of the endocannabinoid system
- Understanding the molecular aspects of THC and CBD as antioxidants
- A tale of two cannabinoids
- Clinical Studies With Cannabis and Cannabinoids, 2005-2009
GLAUCOMA
Glaucoma and CBD Research
- Neuroprotective effect of (-)Delta9-THC and CBD in N-methyl-D-aspartate-induced retinal neurotoxicity
- Effect of sublingual application of cannabinoids on intraocular pressure
HEADACHES & MIGRAINES
Studies on Headaches and the Endocannabinoid Deficiency
- Clinical endocannabinoid deficiency (CECD): Can this concept explain therapeutic benefits of cannabis in migraine, fibromyalgia, irritable bowel syndrome and other treatment-resistant conditions?
- Effects of anandamide in migraine: data from an animal model
- Cannabinoids and hallucinogens for headache
- The endocannabinoid system and migraine
- Variations in the cannabinoid receptor 1 gene predispose to migraine
HEART DISEASE
CBD and Heart Heath Research
- CBD as an anti-arrhythmic, the role of the CB1 receptors
- Is the cardiovascular system a therapeutic target for CBD?
- Acute administration of CBD in vivo suppresses ischaemia-induced cardiac arrhythmias and reduces infarct size when given at reperfusion
- CBD attenuates cardiac dysfunction, oxidative stress, fibrosis, and inflammatory and cell death signaling pathways in diabetic cardiomyopathy
- The Effect of CBD on Ischemia/Reperfusion-Induced Ventricular Arrhythmias
- CBD protects against myocardial ischemic reperfusion injury
- Endocannabinoids acting at cannabinoid-1 receptors regulate cardiovascular function in hypertension
- Oleamide: A fatty acid amide signaling molecule in the cardiovascular system?
- Cannabidiol Protects against Doxorubicin-Induced Cardiomyopathy by Modulating Mitochondrial Function and Biogenesis
HUNTINGTON'S DISEASE
Neuroprotective Attributes of CBD on Huntington's Disease Research
- Neuroprotective effects of phytocannabinoid-based medicines in experimental models of Huntington’s disease
- Cannabinoids: Novel medicines for the treatment of Huntington’s disease
- Sativex-like combination of phytocannabinoids is neuroprotective in malonate-lesioned rats, an inflammatory model of Huntington’s disease: role of CB(1) and CB(2) receptors
- Controlled clinical trial of cannabidiol in Huntington’s disease
- Prospects for cannabinoid therapies in basal ganglia disorders
- Neuroprotective Properties of Cannabigerol in Huntington’s Disease: Studies in R6/2 Mice and 3-Nitropropionate-lesioned Mice
- Effects of a Sativex-Like Combination of Phytocannabinoids on Disease Progression in R6/2 Mice, an Experimental Model of Huntington’s Disease
- Neurological aspects of medical use of CBD
INFLAMMATION & SWELLING
Inflammation of Body Parts and CBD Research
- Cannabidiol as an emergent therapeutic strategy for lessening the impact of inflammation on oxidative stress
- Anti-inflammatory role of cannabidiol and O-1602 in cerulein-induced acute pancreatitis in mice
- The endocannabinoid system: an emerging key player in inflammation
- Cannabinoids, endocannabinoids, and related analogs in inflammation
- Cannabidiol, a non-psychotropic plant-derived cannabinoid, decreases inflammation in a murine model of acute lung injury: role for the adenosine A(2A) receptor
- Cannabinoids suppress inflammatory and neuropathic pain by targeting α3 glycine receptors
- Cannabidiol reduces intestinal inflammation through the control of neuroimmune axis
- Diabetic retinopathy: Role of inflammation and potential therapies for anti-inflammation
- Cannabidiol reduces Aβ-induced neuroinflammation and promotes hippocampal neurogenesis through PPARγ involvement
- Cannabidiol attenuates high glucose-induced endothelial cell inflammatory response and barrier disruption
- Vanilloid TRPV1 receptor mediates the antihyperalgesic effect of the nonpsychoactive cannabinoid, cannabidiol, in a rat model of acute inflammation
- Cannabidiol attenuates cisplatin-induced nephrotoxicity by decreasing oxidative/nitrosative stress, inflammation, and cell death
- Cannabinoids in clinical practice
- Pure THC-V inhibits nitrite production in murine peritoneal macrophages
- Cannabinoids, inflammation, and fibrosis
- Amyloid proteotoxicity initiates an inflammatory response blocked by cannabinoids
- Endocannabinoid 2-arachidonoylglycerol protects inflammatory insults from sulfur dioxide inhalation via cannabinoid receptors in the brain
- Protective effect of CBD on hydrogen peroxide‑induced apoptosis, inflammation and oxidative stress in nucleus pulposus cell
Elevated Sebum Production and Inflammation of the Sebaceous Glands
- The safety and efficacy of 3% Cannabis seeds extract cream for reduction of human cheek skin sebum and erythema content
- CBD as a Treatment for Acne?
- CBD exerts sebostatic and antiinflammatory effects on human sebocytes
- The endocannabinoid system of the skin in health and disease
- Endocannabinoids enhance lipid synthesis and apoptosis of human sebocytes via cannabinoid receptor-2-mediated signaling
- Endocannabinoid signaling and epidermal differentiation
- Differential effectiveness of selected non-psychotropic phytocannabinoids on human sebocyte functions
KIDNEY DISEASE
LIVER DISEASE & HEPATITIS & CIRROSIS
Liver Disease, Cirrosis, and Hepatitis and CBD Research
- The endocannabinoid system and liver diseases
- Cannabidiol protects against hepatic ischemia/reperfusion injury by attenuating inflammatory signaling and response, oxidative/nitrative stress, and cell death
- Cannabidiol causes activated hepatic stellate cell death through a mechanism of endoplasmic reticulum stress-induced apoptosis
- Therapeutic potential of cannabidiol against ischemia/reperfusion liver injury in rats
- Role of myeloid-derived suppressor cells in amelioration of experimental autoimmune hepatitis following activation ofTRPV1 receptors by cannabidiol
- Cannabidiol improves brain and liver function in a fulminant hepatic failure-induced model of hepatic encephalopathy in mice
- Cannabidiol ameliorates cognitive and motor impairments in mice with bile duct ligation
- Potential of CBD for the Treatment of Viral Hepatitis
MULTIPLE SCLEROSIS
Neurological Aspects of Cannabinoids on Multiple Sclerosis
- Sativex for the management of multiple sclerosis symptoms
- THC & CBD oromucosal spray (Sativex®) in the management of spasticity associated with multiple sclerosis
- Clinical efficacy and effectiveness of Sativex, a combined cannabinoid medicine, in multiple sclerosis-related spasticity
- CBD provides long-lasting protection against the deleterious effects of inflammation in a viral model of multiple sclerosis: A role for A2A receptors
- Oromucosal delta9-THC/CBD for neuropathic pain associated with multiple sclerosis
- Nabiximols in the treatment of spasticity, pain and urinary symptoms due to multiple sclerosis
- Sativex long-term use: An open-label trial in patients with spasticity due to multiple sclerosis
- A double-blind, randomized, placebo-controlled, parallel-group study of Sativex, in subjects with symptoms of spasticity due to multiple sclerosis
- Meta-analysis of cannabis based treatments for neuropathic and multiple sclerosis-related pain
- Sativex: Clinical efficacy and tolerability in the treatment of symptoms of multiple sclerosis and neuropathic pain
- Evaluating Sativex in Neuropathic Pain Management
- CBD counteracted the development of experimental MS
- CBD/THC Oromucosal Spray for Multiple Sclerosis-Related Resistant Spasticity in Daily Practice
- Neurological aspects of medical use of CBD
NAUSEA
CBD and Nausea Research
- Regulation of nausea and vomiting by cannabinoids and the endocannabinoid system
- CBD, a non-psychotropic component of cannabis, attenuates vomiting and nausea-like behaviour via indirect agonism of 5-HT(1A) somatodendritic autoreceptors in the dorsal raphe nucleus
- Cannabidiolic acid prevents vomiting in Suncus murinus and nausea-induced behaviour in rats by enhancing 5-HT1Areceptor activation
- Interaction between non-psychotropic cannabinoids in marihuana: effect of cannabigerol (CBG) on the anti-nausea or anti-emetic effects of cannabidiol (CBD) in rats and shrews
- Regulation of nausea and vomiting by cannabinoids
- CBD: its synthetic dimethylheptyl homolog suppress nausea in an experimental model with rats
- Preliminary efficacy and safety of an oromucosal standardized cannabis extract in chemotherapy-induced nausea and vomiting
PAIN
CBD Oil and Pain Management Medical Research
- Investigation of Cannabis for Chronic Pain and Palliative Care
- Cannabinoids in the management of difficult to treat pain
- An open-label extension study to investigate the long-term safety and tolerability of THC/CBD oromucosal spray and oromucosal THC spray in patients with terminal cancer-related pain refractory to strong opioid analgesics.
- A double-blind, randomized, placebo-controlled, parallel-group study of THC/CBD oromucosal spray in combination with the existing treatment regimen, in the relief of central neuropathic pain in patients with multiple sclerosis.
- Pain relief with cannabinoids– the importance of endocannabinoids and cannabinoids for pain therapy
- Meta analysis of cannabis based treatments for neuropathic and multiple sclerosis-related pain
- Marijuana component could ease pain from chemotherapy drugs, study suggests
- Cannabis 101: THC and CBD
- Pain Management without Side Effects: Curing a Schedule II Habit with a Schedule I Plant-Role of the Cannabinoid System in Pain Control and Therapeutic Implications for the Management of Acute and Chronic Pain Episodes
- How Hemp Oil is changing Chronic Pain Management
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FOOD AND DRUG ADMINISTRATION (FDA) DISCLOSURE
Representations regarding the efficacy and safety of CBDPure CBD have not been evaluated by the Food and Drug Administration. The FDA only evaluates foods and drugs, not supplements like these products. These products are not intended to diagnose, prevent, treat, or cure any disease. Click here and here to find evidence of a test, analysis, research, or study describing the benefits, performance or efficacy of CBD Oil based on the expertise of relevant professionals.
These statements have not been evaluated by the FDA and are not intended to diagnose, treat, or cure any disease. Always check with your physician before starting a new dietary supplement program.
The Cannabidiol (CBD) in CBDPure CBD is a natural constituent of industrial hemp plant and legally imported. CBDPure CBD does not sell or distribute any products that are in violation of the United States Controlled Substances Act (US CSA). Since our suppliers provide us with CBD (cannabidiol) extract hemp oil from imported Industrial Hemp with 0.3% or less of the natural THC component, the DEA’s December 13, 2016 Amended Rule does not impair the selling of our CBD Extract.
Safety Information:- Keep out of reach of children.
- This product is not meant for individuals with a history of heart conditions.
- Do not take if pregnant or nursing.
- Consult your physician before starting a new dietary supplement.
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